Fight to Launch the Nukes
You may be a general, have a nuclear keycard, and all the essential code pieces but even so, launching a nuke will be no easy task. The automated defenses of the silo are still very active and very tough. Unless you have a misileer to guide you (all of which are long gone in post apocalyptic Appalachia) the automated defenses will attack on sight.
Being mostly level 50 Assualtrons and sentry bots, you should come prepared for a fight. Bringing a group is obviously the ideal solution.
Next up is Fallout 76 Explore the Nuclear Fallout
You may also be interested in: