Lord Osmund Saddler fight – RE4R
Once you jump on the elevator, it’s time to fight. Saddler has four big weak points – the eyes on his legs. As soon as he drops down, detonate the red barrel near the start and you will be able to take out one or perhaps even two eyes at once. Once the eyes are down, Saddler’s head will lower, giving you a chance to either unload bullets into his mouth-eye thing, or go for a melee stab.
The arena is one of the toughest parts of this fight, as Saddler will break bridges, making it tough to run. There are supplies to find, but you might struggle to find a chance to grab them. You can drop down the ledge either next to where you start, or on the other side of this raised platform. The drop next to the start can’t be escaped from aside from a bridge which must be raised, is timed, and won’t go back up immediately, so it can put you in a very bad position.
The other drop has a ladder to get back up, and another raised area you can climb to get to the other side of the structure. This side of the arena is definitely the safest in terms of space to move.
Saddler has multiple swipe attacks, which will give you a dodge prompt. He also has two long-range attacks where he spits mucus. The horizontal version of this attack can be crouched under, though you should watch for a second burst. The vertical version of this attack can only be dodged while strafing.
Saddler will summon Novistadors during the fight, which is going to make things more difficult, though they will luckily die with just a single hit. Make sure to keep yourself healed, aim for the eyes, and pick up as much as you can in terms of supplies.
Eventually, Saddler will go down, leaving just a big glowing orb thing. Now you need to unload all of your remaining bullets while avoiding some tentacles. You’ll get dodge prompts, and if a tentacle appears on the left, you should strafe to the right, and vice versa.
Ada will throw down a rocket launcher. Grab it and fire it right at the orb. That’ll take down Osmund Saddler for good.